Bafilomycin a1 chloroquine

CQ diffuses into lysosomes and undergoes protonation, while BafA inhibits the ability of the vacuolar type H + -ATPase (v-ATPase) to transfer protons into the lysosome. Although there are many V-ATPase structures reported, the Bafilomycin A1 and chloroquine are commonly used compounds that inhibit autophagy by targeting the lysosomes but through distinct mechanisms

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  2. 7) nor in- and was Bax-independent (Fig
  3. g